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Applied Surrogate Endpoint Evaluation Methods with SAS and R

Alonso, Ariel Shkedy, Ziv Van der Elst, Wim Burzykowski, Tomasz Bigirumurame, Theophile Perualila, Nolen Joy Buyse, Marc

Chapman & Hall/CRC Biostatistics Series

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Leveringstid: 7-30 dager

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An important factor that affects the duration, complexity and cost of a clinical trial is the endpoint used to study the treatments efficacy. When a true endpoint is difficult to use because of such factors as long follow-up times or prohibitive cost, it is sometimes possible to use a surrogate endpoint that can be measured in a more convenient or cost-effective way. This book focuses on the use of surrogate endpoint evaluation methods in practice, using SAS and R.

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