Practical Medicinal Chemistry with Macrocycles : Design, Synthesis, and Case Studies

Omtale

Including case studies of macrocyclic marketed drugs and macrocycles in drug development, this book helps medicinal chemists deal with the synthetic and conceptual challenges of macrocycles in drug discovery efforts. Provides needed background to build a program in macrocycle drug discovery –design criteria, macrocycle profiles, applications, and limitationsFeatures chapters contributed from leading international figures involved in macrocyclic drug discovery effortsCovers design criteria, typical profile of current macrocycles, applications, and limitations